Answered

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Why does sickle cell anemia remain more prevalent in Sub-Saharan Africa than in the rest of the world?
A. The prevalence of malaria in Sub-Saharan Africa provided a selective advantage to individuals who were heterozygous.
B. People of African ancestry are genetically predisposed to carry the sickle cell allele.
C. Infection with malaria provides a selective disadvantage to individuals who are heterozygous for the sickle cell allele.
D. Reduced access to medical facilities predisposes Sub-Saharan Africans to an increased chance of disease.​

Sagot :

youareincredible

Letter A.

Individuals in Sub-Saharan Africa with sickle cell anemia have some protection against malaria, which is common in the region. This has helped the disease remain more prevalent there compared to other parts of the world.

MrChris

[tex]\underline{\underline{\large{\green{\cal{EXPLANATION:}}}}}[/tex]

Despite the immediate deleterious effect on health, the high incidence of sickle cell anemia in Sub-Saharan Africa is attributed to a genetic advantage that makes the patients resistant to severe malaria.

 

The genetic mutation that caused sickle cell anemia was first identified in Africa. Indeed, in areas like Sub-Saharan Africa, where malaria is prevalent and common, individuals with this gene for sickle cell production survive better than those with the normal gene.

A person who is a carrier of the sickle cell anemia gene has a lesser risk of severe malaria, and thus, he or she will have better health and, consequently, more opportunities to procreate.

 

Lack of health care facilities and low health literacy are major reasons closely linked to high levels of early deaths in the Sub-Saharan African region.

Many children born with the disease are unable to receive timely and adequate treatments, so they pass away before the age of five.

Final Answer:

A. The prevalence of malaria in Sub-Saharan Africa provided a selective advantage to individuals who were heterozygous.

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